T-bet Expression by Foxp3(+) T Regulatory Cells is Not Essential for Their Suppressive Function in CNS Autoimmune Disease or Colitis

Accumulation of T regulatory (Treg) cells within the central nervous system (CNS) during experimental autoimmune encephalomyelitis (EAE) is essential for the resolution of disease. CNS Treg cells have been shown to uniformly express the Th1-associated molecules, T-bet and CXCR3. Here, we report that...

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Udgivet i:Front Immunol
Main Authors: McPherson, Rhoanne C., Turner, Darryl G., Mair, Iris, O’Connor, Richard A., Anderton, Stephen M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2015
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332357/
https://ncbi.nlm.nih.gov/pubmed/25741342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00069
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