T-bet Expression by Foxp3(+) T Regulatory Cells is Not Essential for Their Suppressive Function in CNS Autoimmune Disease or Colitis

Accumulation of T regulatory (Treg) cells within the central nervous system (CNS) during experimental autoimmune encephalomyelitis (EAE) is essential for the resolution of disease. CNS Treg cells have been shown to uniformly express the Th1-associated molecules, T-bet and CXCR3. Here, we report that...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: McPherson, Rhoanne C., Turner, Darryl G., Mair, Iris, O’Connor, Richard A., Anderton, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4332357/
https://ncbi.nlm.nih.gov/pubmed/25741342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00069
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