IL-23R–activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity

The factors that promote the differentiation of pathogenic T cells in autoimmune diseases are poorly defined. Use of genetically modified mice has provided insight into molecules necessary for the development of autoimmunity, but the sum of the data has led to contradictory observations based on wha...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Lee, Priscilla W., Smith, Alan J., Yang, Yuhong, Selhorst, Amanda J., Liu, Yue, Racke, Michael K., Lovett-Racke, Amy E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2017
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621925/
https://ncbi.nlm.nih.gov/pubmed/28878115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91663
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