IL-23R–activated STAT3/STAT4 is essential for Th1/Th17-mediated CNS autoimmunity

The factors that promote the differentiation of pathogenic T cells in autoimmune diseases are poorly defined. Use of genetically modified mice has provided insight into molecules necessary for the development of autoimmunity, but the sum of the data has led to contradictory observations based on wha...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Lee, Priscilla W., Smith, Alan J., Yang, Yuhong, Selhorst, Amanda J., Liu, Yue, Racke, Michael K., Lovett-Racke, Amy E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5621925/
https://ncbi.nlm.nih.gov/pubmed/28878115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.91663
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