T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

The extent to which myelin-specific Th1 and Th17 cells contribute to the pathogenesis of experimental autoimmune encephalomyelitis (EAE) is controversial. Combinations of interleukin (IL)-1β, IL-6, and IL-23 with transforming growth factor β were used to differentiate myelin-specific T cell receptor...

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Autori principali: Yang, Yuhong, Weiner, Jeffrey, Liu, Yue, Smith, Alan J., Huss, David J., Winger, Ryan, Peng, Haiyan, Cravens, Petra D., Racke, Michael K., Lovett-Racke, Amy E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715092/
https://ncbi.nlm.nih.gov/pubmed/19546248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20082584
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