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Generation of Guanine – Amino Acid Cross-Links by a Free Radical Combination Mechanism
A direct method has been developed for the in vitro synthesis of stable DNA – protein cross-links (DPC’s) between guanine and amino acids (lysine, arginine). This method employs the combination of guanine neutral radicals, G(-H)(•), and side-chain C-centered amino acid radicals. The latter were gene...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4068030/ https://ncbi.nlm.nih.gov/pubmed/24810398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cp00675e |
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