Oxidation of Guanine by Carbonate Radicals Derived from Photolysis of Carbonatotetramminecobalt(III) Complexes and the pH Dependence of Intrastrand DNA Cross-links Mediated by Guanine Radical Reactions

The carbonate radical anion CO(3)(•−) is a decomposition product of nitrosoperoxycarbonate derived from the combination of carbon dioxide and peroxynitrite, an important biological byproduct of the inflammatory response. The selective oxidation of guanine in DNA by CO(3)(•−) radicals is known to yie...

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Päätekijät: Crean, Conor, Lee, Young Ae, Yun, Byeong Hwa, Geacintov, Nicholas E., Shafirovich, Vladimir
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477471/
https://ncbi.nlm.nih.gov/pubmed/18655084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800105
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