Oxidation of Guanine by Carbonate Radicals Derived from Photolysis of Carbonatotetramminecobalt(III) Complexes and the pH Dependence of Intrastrand DNA Cross-links Mediated by Guanine Radical Reactions

The carbonate radical anion CO(3)(•−) is a decomposition product of nitrosoperoxycarbonate derived from the combination of carbon dioxide and peroxynitrite, an important biological byproduct of the inflammatory response. The selective oxidation of guanine in DNA by CO(3)(•−) radicals is known to yie...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Crean, Conor, Lee, Young Ae, Yun, Byeong Hwa, Geacintov, Nicholas E., Shafirovich, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477471/
https://ncbi.nlm.nih.gov/pubmed/18655084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800105
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge