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Intrastrand G-U cross-links generated by the oxidation of guanine in 5'-d(GCU) and 5'-r(GCU)

It has been suggested that carbonate radical anions are biologically important because they may be produced during the inflammatory response. The carbonate radicals can selectively oxidize guanine in DNA and RNA by one-electron transfer mechanisms and the guanine radicals thus formed decay by divers...

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Библиографические подробности
Главные авторы: Crean, Conor, Geacintov, Nicholas E., Shafirovich, Vladimir
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577587/
https://ncbi.nlm.nih.gov/pubmed/18692567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.07.008
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