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Generation of Guanine – Thymidine Cross-links in DNA by Peroxynitrite/Carbon Dioxide
Nitrosoperoxycarbonate derived from the combination of carbon dioxide and peroxynitrite, is an important chemical mediator of inflammation. In aqueous solutions, it rapidly decomposes to the reactive species CO(3)(•−) and (•)NO(2) radicals that are known to initiate the selective oxidation and nitra...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3138886/ https://ncbi.nlm.nih.gov/pubmed/21513308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200139c |
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