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The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA

Alternative splicing of the oncogene MDM2 is a phenomenon that occurs in cells in response to genotoxic stress and is also a hallmark of several cancer types with important implications in carcinogenesis. However, the mechanisms regulating this splicing event remain unclear. Previously, we uncovered...

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Autori principali: Jacob, Aishwarya G., Singh, Ravi K., Mohammad, Fuad, Bebee, Thomas W., Chandler, Dawn S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
RNA
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4067169/
https://ncbi.nlm.nih.gov/pubmed/24798327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.554717
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