Intron retention as a component of regulated gene expression programs

Por Jacob, Aishwarya G., Smith, Christopher W. J.
Publicado no Hum Genet (2017)

Advances in pediatric rhabdomyosarcoma characterization and disease model development

Por Brien, Dennis O’, Jacob, Aishwarya G., Qualman, Stephen J., Chandler, Dawn S.
Publicado em 2012

The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA

Por Jacob, Aishwarya G., Singh, Ravi K., Mohammad, Fuad, Bebee, Thomas W., Chandler, Dawn S.
Publicado em 2014

Splicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage

Por Comiskey, Daniel F., Jacob, Aishwarya G., Singh, Ravi K., Tapia-Santos, Aixa S., Chandler, Dawn S.
Publicado no Nucleic Acids Res (2015)

Stress-Induced Alternative Splice Forms of MDM2 and MDMX Modulate the p53-Pathway in Distinct Ways

Por Jacob, Aishwarya G., Singh, Ravi K., Comiskey, Daniel F., Rouhier, Matthew F., Mohammad, Fuad, Bebee, Thomas W., Chandler, Dawn S.
Publicado em 2014

Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers

Por Nakagaki-Silva, Erick E, Gooding, Clare, Llorian, Miriam, Jacob, Aishwarya G, Richards, Frederick, Buckroyd, Adrian, Sinha, Sanjay, Smith, Christopher WJ
Publicado no eLife (2019)

A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo

Por Comiskey, Daniel F., Jacob, Aishwarya G., Sanford, Brianne L., Montes, Matías, Goodwin, Andrew K., Steiner, Haley, Matsa, Eleftheria, Tapia-Santos, Aixa S., Bebee, Thomas W., Grieves, Jessica, La Perle, Krista, Boyaka, Prosper, Chandler, Dawn S.
Publicado no Oncogene (2017)

Stress-Induced Isoforms of MDM2 and MDM4 Correlate with High-Grade Disease and an Altered Splicing Network in Pediatric Rhabdomyosarcoma

Por Jacob, Aishwarya G, O'Brien, Dennis, Singh, Ravi K, Comiskey, Daniel F, Littleton, Robert M, Mohammad, Fuad, Gladman, Jordan T, Widmann, Maria C, Jeyaraj, Selvi C, Bolinger, Cheryl, Anderson, James R, Barkauskas, Donald A, Boris-Lawrie, Kathleen, Chandler, Dawn S
Publicado em 2013