Identification of RBPMS as a mammalian smooth muscle master splicing regulator via proximity of its gene with super-enhancers

Alternative splicing (AS) programs are primarily controlled by regulatory RNA-binding proteins (RBPs). It has been proposed that a small number of master splicing regulators might control cell-specific splicing networks and that these RBPs could be identified by proximity of their genes to transcrip...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Nakagaki-Silva, Erick E, Gooding, Clare, Llorian, Miriam, Jacob, Aishwarya G, Richards, Frederick, Buckroyd, Adrian, Sinha, Sanjay, Smith, Christopher WJ
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Chromosomes and Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6613909/
https://ncbi.nlm.nih.gov/pubmed/31283468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.46327
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