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The GTPase-activating protein GIT2 protects against colitis by negatively regulating Toll-like receptor signaling

G protein-coupled receptor kinase-interactor 2 (GIT2) regulates thymocyte positive selection, neutrophil-direction sensing, and cell motility during immune responses by regulating the activity of the small GTPases ADP ribosylation factors (Arfs) and Ras-related C3 botulinum toxin substrate 1 (Rac1)....

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Detalhes bibliográficos
Main Authors: Wei, Juncheng, Wei, Chao, Wang, Min, Qiu, Xiao, Li, Yang, Yuan, Yanzhi, Jin, Chaozhi, Leng, Ling, Wang, Jian, Yang, Xiaoming, He, Fuchu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066529/
https://ncbi.nlm.nih.gov/pubmed/24879442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309218111
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