Cathelicidin Signaling via the Toll-Like Receptor Protects Against Colitis in Mice

BACKGROUND & AIMS: Cathelicidin (encoded by Camp) is an anti-microbial peptide in the innate immune system. We examined whether macrophages express cathelicidin in colons of mice with experimental colitis and patients with inflammatory bowel disease; we investigated its signaling mechanisms. MET...

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Detalhes bibliográficos
Main Authors: Koon, Hon Wai, Shih, David Quan, Chen, Jeremy, Bakirtzi, Kyriaki, Hing, Tressia C, Law, Ivy, Ho, Samantha, Ichikawa, Ryan, Zhao, Dezheng, Xu, Hua, Gallo, Richard, Dempsey, Paul, Cheng, Genhong, Targan, Stephan R, Pothoulakis, Charalabos
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199285/
https://ncbi.nlm.nih.gov/pubmed/21762664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.079
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