Cathelicidin Signaling via the Toll-Like Receptor Protects Against Colitis in Mice

BACKGROUND & AIMS: Cathelicidin (encoded by Camp) is an anti-microbial peptide in the innate immune system. We examined whether macrophages express cathelicidin in colons of mice with experimental colitis and patients with inflammatory bowel disease; we investigated its signaling mechanisms. MET...

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Auteurs principaux: Koon, Hon Wai, Shih, David Quan, Chen, Jeremy, Bakirtzi, Kyriaki, Hing, Tressia C, Law, Ivy, Ho, Samantha, Ichikawa, Ryan, Zhao, Dezheng, Xu, Hua, Gallo, Richard, Dempsey, Paul, Cheng, Genhong, Targan, Stephan R, Pothoulakis, Charalabos
Format: Artigo
Langue:Inglês
Publié: 2011
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199285/
https://ncbi.nlm.nih.gov/pubmed/21762664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.06.079
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