Acute Administration of Unacylated Ghrelin Has No Effect on Basal or Stimulated Insulin Secretion in Healthy Humans

Unacylated ghrelin (UAG) is the predominant ghrelin isoform in the circulation. Despite its inability to activate the classical ghrelin receptor, preclinical studies suggest that UAG may promote β-cell function. We hypothesized that UAG would oppose the effects of acylated ghrelin (AG) on insulin se...

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Autores principales: Tong, Jenny, Davis, Harold W., Summer, Suzanne, Benoit, Stephen C., Haque, Ahrar, Bidlingmaier, Martin, Tschöp, Matthias H., D’Alessio, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2014
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4066344/
https://ncbi.nlm.nih.gov/pubmed/24550190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1598
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