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Ghrelin Suppresses Glucose-Stimulated Insulin Secretion and Deteriorates Glucose Tolerance in Healthy Humans

OBJECTIVE: The orexigenic gut hormone ghrelin and its receptor are present in pancreatic islets. Although ghrelin reduces insulin secretion in rodents, its effect on insulin secretion in humans has not been established. The goal of this study was to test the hypothesis that circulating ghrelin suppr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tong, Jenny, Prigeon, Ronald L., Davis, Harold W., Bidlingmaier, Martin, Kahn, Steven E., Cummings, David E., Tschöp, Matthias H., D'Alessio, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927935/
https://ncbi.nlm.nih.gov/pubmed/20584998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0504
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