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Ghrelin Impairs Prandial Glucose Tolerance and Insulin Secretion in Healthy Humans Despite Increasing GLP-1

OBJECTIVES: Administration of ghrelin inhibits the acute insulin response to glucose and worsens IV glucose tolerance in healthy subjects. Evidence from preclinical studies suggests that ghrelin may have differential effects on glucose metabolism during fasting and feeding. Our objective was to test...

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Bibliografische gegevens
Gepubliceerd in:J Clin Endocrinol Metab
Hoofdauteurs: Tong, Jenny, Davis, Harold W., Gastaldelli, Amalia, D'Alessio, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891805/
https://ncbi.nlm.nih.gov/pubmed/27055279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-4154
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