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Ghrelin Impairs Prandial Glucose Tolerance and Insulin Secretion in Healthy Humans Despite Increasing GLP-1

OBJECTIVES: Administration of ghrelin inhibits the acute insulin response to glucose and worsens IV glucose tolerance in healthy subjects. Evidence from preclinical studies suggests that ghrelin may have differential effects on glucose metabolism during fasting and feeding. Our objective was to test...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Tong, Jenny, Davis, Harold W., Gastaldelli, Amalia, D'Alessio, David
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891805/
https://ncbi.nlm.nih.gov/pubmed/27055279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-4154
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