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Intramitochondrial Zn(2+) accumulation via the Ca(2+) uniporter contributes to acute ischemic neurodegeneration
Ca(2+) and Zn(2+) have both been implicated in the induction of acute ischemic neurodegeneration. We recently examined changes in intracellular Zn(2+) and Ca(2+) in CA1 pyramidal neurons subjected to oxygen glucose deprivation (OGD), and found that Zn(2+) rises precede and contribute to the onset of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065779/ https://ncbi.nlm.nih.gov/pubmed/24787898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.04.011 |
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