Differential Vulnerability of CA1 versus CA3 Pyramidal Neurons After Ischemia: Possible Relationship to Sources of Zn(2+) Accumulation and Its Entry into and Prolonged Effects on Mitochondria

Excitotoxic mechanisms contribute to the degeneration of hippocampal pyramidal neurons after recurrent seizures and brain ischemia. However, susceptibility differs, with CA1 neurons degenerating preferentially after global ischemia and CA3 neurons after limbic seizures. Whereas most studies address...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Medvedeva, Yuliya V., Ji, Sung G., Yin, Hong Z., Weiss, John H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2017
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5242414/
https://ncbi.nlm.nih.gov/pubmed/28100752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3270-16.2016
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