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Rapid Intramitochondrial Zn(2+) Accumulation in CA1 Hippocampal Pyramidal Neurons After Transient Global Ischemia: A Possible Contributor to Mitochondrial Disruption and Cell Death

Mitochondrial Zn(2+) accumulation, particularly in CA1 neurons, occurs after ischemia and likely contributes to mitochondrial dysfunction and subsequent neurodegeneration. However, the relationship between mitochondrial Zn(2+) accumulation and their disruption has not been examined at the ultrastruc...

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Detalhes bibliográficos
Publicado no:J Neuropathol Exp Neurol
Main Authors: Yin, Hong Z, Wang, Hwai-Lee, Ji, Sung G, Medvedeva, Yuliya V, Tian, Guilian, Bazrafkan, Afsheen K, Maki, Niki Z, Akbari, Yama, Weiss, John H
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581555/
https://ncbi.nlm.nih.gov/pubmed/31150090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlz042
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