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Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development

Muscarinic acetylcholine receptor antagonists are widely used as bronchodilating drugs in pulmonary medicine. The therapeutic efficacy of these agents depends on the blockade of M(3) muscarinic receptors expressed on airway smooth muscle cells. All muscarinic antagonists currently used as bronchodil...

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Bibliografiska uppgifter
Huvudupphovsmän: Kruse, Andrew C., Hu, Jianxin, Kobilka, Brian K., Wess, Jürgen
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065632/
https://ncbi.nlm.nih.gov/pubmed/24662799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2014.02.006
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