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Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development
Muscarinic acetylcholine receptor antagonists are widely used as bronchodilating drugs in pulmonary medicine. The therapeutic efficacy of these agents depends on the blockade of M(3) muscarinic receptors expressed on airway smooth muscle cells. All muscarinic antagonists currently used as bronchodil...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4065632/ https://ncbi.nlm.nih.gov/pubmed/24662799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2014.02.006 |
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