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Specific Binding, Uptake, and Transport of ICAM-1-Targeted Nanocarriers Across Endothelial and Subendothelial Cell Components of the Blood-Brain Barrier

PURPOSE: The blood-brain barrier (BBB) represents a target for therapeutic intervention and an obstacle for brain drug delivery. Targeting endocytic receptors on brain endothelial cells (ECs) helps transporting drugs and carriers into and across this barrier. While most receptors tested are associat...

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Autors principals: Hsu, Janet, Rappaport, Jeff, Muro, Silvia
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065215/
https://ncbi.nlm.nih.gov/pubmed/24558007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1289-8
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