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Inactivation of MYC reverses tumorigenesis

The MYC proto-oncogene is an essential regulator of many normal biological programmes. MYC, when activated as an oncogene, has been implicated in the pathogenesis of most types of human cancers. MYC overexpression in normal cells is restrained from causing cancer through multiple genetically and epi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, Yulin, Casey, Stephanie C., Felsher, Dean W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065197/
https://ncbi.nlm.nih.gov/pubmed/24645771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/joim.12237
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