Sequestration of multiple RNA recognition motif-containing proteins by C9orf72 repeat expansions

GGGGCC repeat expansions of C9orf72 represent the most common genetic variant of amyotrophic lateral sclerosis and frontotemporal degeneration, but the mechanism of pathogenesis is unclear. Recent reports have suggested that the transcribed repeat might form toxic RNA foci that sequester various RNA...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Cooper-Knock, Johnathan, Walsh, Matthew J., Higginbottom, Adrian, Robin Highley, J., Dickman, Mark J., Edbauer, Dieter, Ince, Paul G., Wharton, Stephen B., Wilson, Stuart A., Kirby, Janine, Hautbergue, Guillaume M., Shaw, Pamela J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
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Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065024/
https://ncbi.nlm.nih.gov/pubmed/24866055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awu120
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