Llwytho...
Alzheimer’s disease therapeutics targeted to the control of amyloid precursor protein translation: Maintenance of brain iron homeostasis
The neurotoxicity of amyloid beta (Aβ), a major cleavage product of the amyloid precursor protein (APP), is enhanced by iron, as found in the amyloid plaques of Alzheimer’s disease (AD) patients. By contrast, the long-known neuroprotective activity of APP is evident after α-secretase cleavage of the...
Wedi'i Gadw mewn:
Prif Awduron: | , |
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Fformat: | Artigo |
Iaith: | Inglês |
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2014
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4064675/ https://ncbi.nlm.nih.gov/pubmed/24513321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.01.032 |
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