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DNA DSB repair pathway choice: an orchestrated handover mechanism

DNA double strand breaks (DSBs) are potential lethal lesions but can also lead to chromosome rearrangements, a step promoting carcinogenesis. DNA non-homologous end-joining (NHEJ) is the major DSB rejoining process and occurs in all cell cycle stages. Homologous recombination (HR) can additionally f...

詳細記述

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書誌詳細
主要な著者: Kakarougkas, A, Jeggo, P A
フォーマット: Artigo
言語:Inglês
出版事項: The British Institute of Radiology. 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4064598/
https://ncbi.nlm.nih.gov/pubmed/24363387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1259/bjr.20130685
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