Factors determining DNA double-strand break repair pathway choice in G2 phase

DNA non-homologous end joining (NHEJ) and homologous recombination (HR) function to repair DNA double-strand breaks (DSBs) in G2 phase with HR preferentially repairing heterochromatin-associated DSBs (HC-DSBs). Here, we examine the regulation of repair pathway usage at two-ended DSBs in G2. We ident...

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Bibliografiske detaljer
Main Authors: Shibata, Atsushi, Conrad, Sandro, Birraux, Julie, Geuting, Verena, Barton, Olivia, Ismail, Amani, Kakarougkas, Andreas, Meek, Katheryn, Taucher-Scholz, Gisela, Löbrich, Markus, Jeggo, Penny A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061033/
https://ncbi.nlm.nih.gov/pubmed/21317870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.27
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