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The optimal rate of chromosome loss for the inactivation of tumor suppressor genes in cancer

Many cancers are characterized by chromosomal instability (CIN). This phenotype involves the deletion and duplication of chromosomes or chromosome parts and results in a high degree of aneuploidy. The role of CIN for cancer progression is a very important, yet unresolved question. It has been argued...

詳細記述

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書誌詳細
主要な著者: Komarova, Natalia L., Wodarz, Dominik
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC406458/
https://ncbi.nlm.nih.gov/pubmed/15105448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401943101
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