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Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

The recently identified PTEN/MMAC1 gene is a candidate tumor suppressor implicated in multiple tumor types based on mutations or homozygous deletions of the gene in certain human cancers. No studies of PTEN/MMAC1 mRNA or protein expression in cancer cells have been reported, primarily because of sig...

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Detalhes bibliográficos
Main Authors: Whang, Young E., Wu, Xinyi, Suzuki, Hiroyoshi, Reiter, Robert E., Tran, Chris, Vessella, Robert L., Said, Jonathan W., Isaacs, William B., Sawyers, Charles L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC20246/
https://ncbi.nlm.nih.gov/pubmed/9560261
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