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Drug resistance in cancer: Principles of emergence and prevention

Although targeted therapy is yielding promising results in the treatment of specific cancers, drug resistance poses a problem. We develop a mathematical framework that can be used to study the principles underlying the emergence and prevention of resistance in cancers treated with targeted small-mol...

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Autors principals: Komarova, Natalia L., Wodarz, Dominik
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1172248/
https://ncbi.nlm.nih.gov/pubmed/15980154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501870102
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