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On the emergence of multifocal cancers

Several tumors can exist as multiple lesions within a tissue. The lesions may either arise independently, or they may be monoclonal. The importance of multiple lesions for tumor staging, progression, and treatment is subject to debate. Here we use mathematical models to analyze the emergence of mult...

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Main Authors: Wodarz, Dominik, Iwasa, Yoh, Komarova, Natalia L
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2004
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC526757/
https://ncbi.nlm.nih.gov/pubmed/15461783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-3-13
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