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On the emergence of multifocal cancers

Several tumors can exist as multiple lesions within a tissue. The lesions may either arise independently, or they may be monoclonal. The importance of multiple lesions for tumor staging, progression, and treatment is subject to debate. Here we use mathematical models to analyze the emergence of mult...

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Autors principals: Wodarz, Dominik, Iwasa, Yoh, Komarova, Natalia L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC526757/
https://ncbi.nlm.nih.gov/pubmed/15461783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3163-3-13
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