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Evolution of ibrutinib resistance in chronic lymphocytic leukemia (CLL)

The Bruton tyrosine kinase inhibitor (BTKi) ibrutinib is a new targeted therapy for patients with chronic lymphocytic leukemia (CLL). Ibrutinib is given orally on a continuous schedule and induces durable remissions in the majority of CLL patients. However, a small proportion of patients initially r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Komarova, Natalia L., Burger, Jan A., Wodarz, Dominik
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183279/
https://ncbi.nlm.nih.gov/pubmed/25201956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409362111
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