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The Drosophila Werner Exonuclease Participates in an Exonuclease-Independent Response to Replication Stress

Members of the RecQ family of helicases are known for their roles in DNA repair, replication, and recombination. Mutations in the human RecQ helicases, WRN and BLM, cause Werner and Bloom syndromes, which are diseases characterized by genome instability and an increased risk of cancer. While WRN con...

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Detalhes bibliográficos
Main Authors: Bolterstein, Elyse, Rivero, Rachel, Marquez, Melissa, McVey, Mitch
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063921/
https://ncbi.nlm.nih.gov/pubmed/24709634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.164228
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