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The Drosophila Werner Exonuclease Participates in an Exonuclease-Independent Response to Replication Stress

Members of the RecQ family of helicases are known for their roles in DNA repair, replication, and recombination. Mutations in the human RecQ helicases, WRN and BLM, cause Werner and Bloom syndromes, which are diseases characterized by genome instability and an increased risk of cancer. While WRN con...

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Hlavní autoři: Bolterstein, Elyse, Rivero, Rachel, Marquez, Melissa, McVey, Mitch
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063921/
https://ncbi.nlm.nih.gov/pubmed/24709634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.164228
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