Evidence for premature aging in a Drosophila model of Werner syndrome

Werner syndrome (WS) is an autosomal recessive progeroid disease characterized by patients’ early onset of aging, increased risk of cancer and other age-related pathologies. WS is caused by mutations in WRN, a RecQ helicase that has essential roles responding to DNA damage and preventing genomic ins...

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Udgivet i:Exp Gerontol
Main Authors: Cassidy, Deirdre, Epiney, Derek, Salameh, Charlotte, Zhou, Luhan T., Salomon, Robert N., Schirmer, Aaron E., McVey, Mitch, Bolterstein, Elyse
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935377/
https://ncbi.nlm.nih.gov/pubmed/31518666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2019.110733
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