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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer
Werner syndrome (WS) is an inherited disorder characterized by premature onset of aging, genomic instability, and increased cancer incidence. The disease is caused by loss of function mutations of the WRN gene, a RecQ family member with both helicase and exonuclease activities. However, despite its...
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| Prif Awduron: | , , , , , , , , , , , , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
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National Academy of Sciences
2006
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| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1466544/ https://ncbi.nlm.nih.gov/pubmed/16723399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600645103 |
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