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A novel Werner Syndrome mutation: pharmacological treatment by read-through of nonsense mutations and epigenetic therapies
Werner Syndrome (WS) is a rare inherited disease characterized by premature aging and increased propensity for cancer. Mutations in the WRN gene can be of several types, including nonsense mutations, leading to a truncated protein form. WRN is a RecQ family member with both helicase and exonuclease...
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| Publicado no: | Epigenetics |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622951/ https://ncbi.nlm.nih.gov/pubmed/25830902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1027853 |
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