The Drosophila melanogaster PIF1 Helicase Promotes Survival During Replication Stress and Processive DNA Synthesis During Double-Strand Gap Repair

PIF1 is a 5′ to 3′ DNA helicase that can unwind double-stranded DNA and disrupt nucleic acid-protein complexes. In Saccharomyces cerevisiae, Pif1 plays important roles in mitochondrial and nuclear genome maintenance, telomere length regulation, unwinding of G-quadruplex structures, and DNA synthesis...

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Bibliographic Details
Published in:Genetics
Main Authors: Kocak, Ece, Dykstra, Sarah, Nemeth, Alexandra, Coughlin, Catherine G., Rodgers, Kasey, McVey, Mitch
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2019
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Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6827366/
https://ncbi.nlm.nih.gov/pubmed/31537623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.119.302665
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