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Smac mimetics combined with innate immune stimuli create the perfect cytokine storm to kill tumor cells

A dual immunotherapy approach employing small-molecule inhibitors of apoptosis (IAP) protein antagonists in combination with innate immune stimuli has proven to be highly synergistic and effective in animal tumor models. This strategy overcomes many of the limitations of either single agent therapy...

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Detalhes bibliográficos
Main Authors: Beug, Shawn T, LaCasse, Eric C, Korneluk, Robert G
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063156/
https://ncbi.nlm.nih.gov/pubmed/25050221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.28541
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