Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model

Rhabdomyosarcoma (RMS), a neoplasm characterized by undifferentiated myoblasts, is the most common soft tissue tumour in children. Therapeutic resistance is common in RMS and is often caused by acquired defects in the cellular apoptotic program. Smac mimetic compounds (SMCs) are a novel class of inh...

Szczegółowa specyfikacja

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Opis bibliograficzny
Wydane w:Oncotarget
Główni autorzy: Dobson, Christine C, Naing, Thet, Beug, Shawn T, Faye, Mame D, Chabot, Janelle, St-Jean, Martin, Walker, Danielle E, LaCasse, Eric C, Stojdl, David F, Korneluk, Robert G, Holcik, Martin
Format: Artigo
Język:Inglês
Wydane: Impact Journals LLC 2016
Hasła przedmiotowe:
Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356898/
https://ncbi.nlm.nih.gov/pubmed/27966453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13849
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