Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model

Rhabdomyosarcoma (RMS), a neoplasm characterized by undifferentiated myoblasts, is the most common soft tissue tumour in children. Therapeutic resistance is common in RMS and is often caused by acquired defects in the cellular apoptotic program. Smac mimetic compounds (SMCs) are a novel class of inh...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Dobson, Christine C, Naing, Thet, Beug, Shawn T, Faye, Mame D, Chabot, Janelle, St-Jean, Martin, Walker, Danielle E, LaCasse, Eric C, Stojdl, David F, Korneluk, Robert G, Holcik, Martin
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356898/
https://ncbi.nlm.nih.gov/pubmed/27966453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13849
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