Oncolytic virus synergizes with Smac mimetic compounds to induce rhabdomyosarcoma cell death in a syngeneic murine model

Rhabdomyosarcoma (RMS), a neoplasm characterized by undifferentiated myoblasts, is the most common soft tissue tumour in children. Therapeutic resistance is common in RMS and is often caused by acquired defects in the cellular apoptotic program. Smac mimetic compounds (SMCs) are a novel class of inh...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dobson, Christine C, Naing, Thet, Beug, Shawn T, Faye, Mame D, Chabot, Janelle, St-Jean, Martin, Walker, Danielle E, LaCasse, Eric C, Stojdl, David F, Korneluk, Robert G, Holcik, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356898/
https://ncbi.nlm.nih.gov/pubmed/27966453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13849
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