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Smac Mimetic Compounds Potentiate Interleukin-1β-mediated Cell Death
Smac mimetic compounds (SMCs) potentiate TNFα-mediated cancer cell death by targeting the inhibitor of apoptosis (IAP) proteins. In addition to TNFα, the tumor microenvironment is exposed to a number of pro-inflammatory cytokines, including IL-1β. Here, we investigated the potential impact of IL-1β...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003360/ https://ncbi.nlm.nih.gov/pubmed/20956527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.183616 |
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