Treatment of FLT3-ITD-Positive Acute Myeloid Leukemia Relapsing after Allogeneic Stem Cell Transplantation with Sorafenib

Patients with acute myeloid leukemia (AML) and internal tandem duplication of FMS-like tyrosine kinase receptor-3 gene (FLT3-ITD) mutation have poor prognoses and are often treated with allogeneic hematopoietic stem cell transplantation (HSCT). Sorafenib, an inhibitor of multiple kinases including F...

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Autori principali: Sharma, Manish, Ravandi, Farhad, Bayraktar, Ulas Darda, Chiattone, Alexandre, Bashir, Qaiser, Giralt, Sergio, Chen, Julianne, Qazilbash, Muzaffar, Kebriaei, Partow, Konopleva, Marina, Andreeff, Michael, Cortes, Jorge, McCue, Deborah, Kantarjian, Hagop, Champlin, Richard E., de Lima, Marcos
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061979/
https://ncbi.nlm.nih.gov/pubmed/21767516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2011.07.011
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