Allogeneic Transplantation in First Remission Improves Outcome Irrespective of FLT3-ITD Allelic Ratio in FLT3-ITD positive AML

Adverse prognosis of internal tandem duplication in the FMS-like tyrosine kinase 3 gene(s) (FLT3-ITD) among AML patients may depend on allelic burden. We compared post-remission therapies of chemotherapy and hematopoietic stem cell transplantation (HSCT) in 169 FLT3-ITDmut intermediate cytogenetic r...

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Pubblicato in:Biol Blood Marrow Transplant
Autori principali: Oran, Betül, Cortes, Jorge, Beitinjaneh, Amer, Chen, Hsiang-Chun, de Lima, Marcos, Patel, Keyur, Ravandi, Farhad, Wang, Xuemei, Brandt, Mark, Andersson, Borje S., Ciurea, Stefan, Santos, Fabio P, de Padua Silva, Leandro, Shpall, Elizabeth J., Champlin, Richard E., Kantarjian, Hagop, Borthakur, Gautam
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201699/
https://ncbi.nlm.nih.gov/pubmed/27058617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2016.03.027
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