Salvage therapy using FLT3 inhibitors may improve long-term outcome of relapsed or refractory AML in patients with FLT3-ITD

To determine the long-term efficacy of FLT3 inhibitors (FLT3i) in the salvage setting for relapsed and refractory (rel/ref) acute myeloid leukemia (AML) with FLT3 internal tandem duplication (AML FLT3-ITD), we conducted a retrospective study of 120 patients with rel/ref AML FLT3-ITD who received sal...

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Main Authors: Takahashi, Koichi, Kantarjian, Hagop, Pemmaraju, Naveen, Andreeff, Michael, Borthakur, Gautam, Faderl, Stefan, Garcia-Manero, Guillermo, Pierce, Sherry, Luthra, Rajyalakshmi, Cardenas-Turanzas, Marylou, Estrov, Zeev, Ravandi, Farhad, Cortes, Jorge
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068703/
https://ncbi.nlm.nih.gov/pubmed/23530930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.12299
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