Structure-Guided Rescaffolding of Selective Antagonists of BCL-X(L)

[Image: see text] Because of the promise of BCL-2 antagonists in combating chronic lymphocytic leukemia (CLL) and non-Hodgkin’s lymphoma (NHL), interest in additional selective antagonists of antiapoptotic proteins has grown. Beginning with a series of selective, potent BCL-X(L) antagonists containi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Koehler, Michael F. T., Bergeron, Philippe, Choo, Edna F., Lau, Kevin, Ndubaku, Chudi, Dudley, Danette, Gibbons, Paul, Sleebs, Brad E., Rye, Carl S., Nikolakopoulos, George, Bui, Chinh, Kulasegaram, Sanji, Kersten, Wilhelmus J. A., Smith, Brian J., Czabotar, Peter E., Colman, Peter M., Huang, David C. S., Baell, Jonathan B., Watson, Keith G., Hasvold, Lisa, Tao, Zhi-Fu, Wang, Le, Souers, Andrew J., Elmore, Steven W., Flygare, John A., Fairbrother, Wayne J., Lessene, Guillaume
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2014
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060937/
https://ncbi.nlm.nih.gov/pubmed/24944740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500030p
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