Design of novel granulopoietic proteins by topological rescaffolding

Computational protein design is rapidly becoming more powerful, and improving the accuracy of computational methods would greatly streamline protein engineering by eliminating the need for empirical optimization in the laboratory. In this work, we set out to design novel granulopoietic agents using...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Biol
Prif Awduron: Hernandez Alvarez, Birte, Skokowa, Julia, Coles, Murray, Mir, Perihan, Nasri, Masoud, Maksymenko, Kateryna, Weidmann, Laura, Rogers, Katherine W., Welte, Karl, Lupas, Andrei N., Müller, Patrick, ElGamacy, Mohammad
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Methods and Resources
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7755208/
https://ncbi.nlm.nih.gov/pubmed/33351791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000919
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