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Control of catalytic efficiency by a coevolving network of catalytic and noncatalytic residues

The active sites of enzymes consist of residues necessary for catalysis and structurally important noncatalytic residues that together maintain the architecture and function of the active site. Examples of evolutionary interactions between catalytic and noncatalytic residues have been difficult to d...

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Sonraí Bibleagrafaíochta
Main Authors: McMurrough, Thomas A., Dickson, Russell J., Thibert, Stephanie M. F., Gloor, Gregory B., Edgell, David R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060692/
https://ncbi.nlm.nih.gov/pubmed/24912189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322352111
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